From the dauer expert lab of Patrick Hu, comes a publication by lead author Albert Chen:
This paper stresses the importance of isoform studies. Chen et al 2015 uncover the role of isoforms in having significant capacity to influence metabolic output. These studies were done when MosSCI was the only tool for single-copy modification of the genome. Now, with the perfection of CRISPR transgenesis, expect these kinds of isoform-specific transgenics to be easier to perform and be more commonplace in the literature.