Humanized model organisms are powerful biological models that allow scientists to study human disease genes in simpler contexts without losing the value of in vivo studies.
In either C. elegans or Zebrafish, a native model organism gene can be replaced by a human gene with the same biological function. Mutations can be introduced into the human gene in order to make a disease variant. Alternatively, the human gene can be expressed in specific tissues or stages of development.
With these models researchers can gain insights into protein function, test therapeutic treatments, and mimic human disease states. Contact us by filling out the form below to see how we can create the humanized models you need for your research.