Knudra Genesis

Knudra

Sanskrit derivative: knu (wet) and dra (run)

 

Knudra Transgenics was formed in late 2009.  Since the first client project completed in early 2010, the Knudra team has been supplying researchers and private entities custom-built transgenics.  Starting first in C elegans then expanding into zebrafish and soon to be mice, Knudra has gained the experience to efficiently get clients the transgenics they need. The Knudra Team has a combined over 30 years of experience in making transgenic organisms. Knudra uses the latest advances in genome engineering to build powerful platforms of medical discovery. Knudra has transformed its passion for genome engineering into a first-in-kind contract research service. Knudra uses technology licensed from the University of Utah to turn a small-model organisms into a platform for biomedical discovery. Our tenacious and highly-skilled team works closely with our clients to help create the tool they need to answer their tough research questions. With over 1000 transgenics delivered to over 200 clients, we have the experience to get you the transgenics that accelerate your science.

Management

 

Trisha Brock

CEO

Trisha is a State of Washington native who joined Knudra in 2010 as a Harvard-trained postdoc. Trisha’s skill set was developed from over 10 years working in genetics, RNAi and qPCR techniques. As a result, her capacity is making profound impact on the efficiencies in transgenesis projects. In business, Trisha’s recent graduation from the exclusive Goldman Sachs 10,000 Small Business mentoring program is being leveraged to improve client experience and achieve greater profitability. As Chief Executive Officer, Trisha brings balance guidance to lead the performance from the business and production teams. Under Trisha’s leadership, Knudra has reached solvency needed for future sustainability of Knudra’s TavaServ platform of services.

 

Chris Hopkins

CSO

Chris founded Knudra in 2009 to commercialize MosSCI transgenesis technology. As a postdoc in the lab of Dr. Erik Jorgensen, Chris has the good fortune to witness and make contributions to the development of the MosSCI transgenesis technique, which was lead by Dr. Christian Frøkjær-Jensen. Chris realized that the art of genome engineering was being commercially served to mice and flies, yet no commercial firm was offering transgenesis service to the worm community. Seizing on the opportunity with receipt of a SBIR contract from the National Institute of Health, Chris pioneered converting the contract work of making nematodes biosensors for the NIEHS into a general service platform to provide custom transgenics to biomedical researchers worldwide. Chris recently obtained a MBA from Westminster College. Chris uses his MBA knowledge to expand marketing and create sales in the broader market of model-organism genome engineering.

 

Zach Stevenson

Mutagenesis Specialist

Zach is expanding our genome editing services. As Mutagenesis Specialist, Zach brings a valuable command of a molecular biology toolset, which is used to improve throughput in the detection of targeted mutations in model organism genomes.

 

Thomas Marshall

Research and Development Scientist 

As Research and Development Scientist, Tom brings a valuable command of a molecular biology toolset. Tom leverages extensive experience in mammalian cell biology and cell culture to develop efficient plasmid design and assembly. 

 

Stelian Pop

Injection Specialist

Stelian joined Knudra to lead expansion of transgenesis services. As Injection Specialist, Stelian directs the implementation of all Transgenic Capture techniques.

Advisory

S. George Simon

Business development

Mr. Simon has over 25 years of worldwide business development, licensing, and product development experience with numerous pharmaceutical, diagnostic and medical device companies. Mr Simon will use his experience in pharma/biotech to negotiate deals with our pharmaceutical partners. Notably, Mr. Simon was the principal negotiator and deal architect for the one of the largest start-up financings in the biotech industry – raising $82 million in a joint venture with Hitachi and Oracle. George Simon brings a wealth of experience to the Knudra team.

 

Erik Jorgensen

Transgenesis Technology

Dr.Erik Jorgensen is a Distinguished Professor of Biology specializing in the genetics of neurotransmission in the nematode C. elegans. Dr. Jorgensen has over 30 years experience probing the genetics of various model organisms to study development and function of nervous systems. In addition to applying and innovating in the tools electrophysiology, super-resolution microscopy and electron microscopy, Dr. Jorgensen’s group developed methods to manipulate the C. elegans genome with a heterologous DNA transposon, the MosSCI method. As a result, Dr. Jorgensen brings a wealth of scientific knowledge in his Advisory Board role at Knudra.

 

Jonathan Baker

Intellectual property

Dr. Jonathan Baker is patent agent specializing in intellectual property in pharmaceutical sciences. Dr. Baker has acquired over 12 years of intellectual property expertise work by first working Senior Patent Agent with Myriad Genetics for 5 years, then as Director of Intellectual Property at Oryzon Genomics for 4 years. Recently, Dr. Baker has worked as an Intellectual Property Development Consultant at Innoventius, LLC for 3 years. Dr. Baker 's extensive IP experience allows him to efficiently and comprehensively direct the capture of Knudra's technology inventions.